35+ Series A Healthcare Startups — $1B Raised, 25 Companies

Series A healthcare startups in 2025-2026 are overwhelmingly AI-powered. Our dataset tracks 25 Series A healthcare companies that raised a combined $1.0B at a $19M median — slightly below the overall Series A median of $21M, reflecting the sector's regulatory complexity. Clinical decision support, prior authorization automation, and AI-assisted diagnostics are the dominant categories. Investors like a16z Bio, NEA, and OrbiMed are deploying significant capital into healthcare AI companies that can demonstrate measurable clinical outcomes. The FDA's evolving framework for AI/ML medical devices has reduced regulatory uncertainty, encouraging more venture investment at the Series A stage. Revenue cycle management and provider credentialing are also attracting Series A capital as healthcare systems prioritize operational efficiency. For GTM teams, these 25 companies with $1.0B in fresh capital are navigating complex purchasing environments — your tools need HIPAA compliance, SOC 2, and ideally HITRUST certification. Target CTO/CIO for technology purchases and VP of Operations for workflow tools. The $19M median budget means these companies can make meaningful software investments.